NSJ Bioreagents
SKU:RQ4616
Cardiac Troponin T Antibody / CTnT / TNNT2
Cardiac Troponin T Antibody / CTnT / TNNT2
Couldn't load pickup availability
Cardiac muscle troponin T (cTnT), is a protein which in humans is encoded by the TNNT2 gene. It is mapped to 1q32.1. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Mouse, Rat |
| Application | WB, Direct ELISA |
| Application Details | Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the Cardiac Troponin T antibody should be determined by the researcher. |
| Immunogen | Amino acids K88-K298 from the human protein were used as the immunogen for the Cardiac Troponin T antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the Cardiac Troponin T antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Uniprot # | P45379 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cardiac-troponin-t-antibody-ctnt-tnnt2-rq4616 |
| Title | Cardiac Troponin T Antibody / CTnT / TNNT2 |
| Description | Cardiac muscle troponin T (cTnT), is a protein which in humans is encoded by the TNNT2 gene. It is mapped to 1q32.1. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. |
Share
