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NSJ Bioreagents

SKU:F54270-0.08ML

Carboxylesterase 2 Antibody / CES2

Carboxylesterase 2 Antibody / CES2

Regular price $205.00 USD
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CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Application WB, IHC-P, FACS
Application Details Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:25,Flow cytometry: 1:25 (1x10e6 cells)
Application Note The stated application concentrations are suggested starting points. Titration of the Carboxylesterase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Localization Cytoplasmic
Immunogen A portion of amino acids 340-369 from the human protein were used as the immunogen for the Carboxylesterase 2 antibody.
Purity Antigen affinity purified
Storage Aliquot the Carboxylesterase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This Carboxylesterase 2 antibody is available for research use only.
Uniprot # O00748
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/carboxylesterase-2-antibody-ces2-f54270
Title Carboxylesterase 2 Antibody / CES2
Description CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.
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