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NSJ Bioreagents
SKU:RQ7262
CANX Antibody / Calnexin
CANX Antibody / Calnexin
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Calnexin, also called CANX and CNX, is a 67 kDa integral protein of the endoplasmic reticulum. This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Clone | 8D10B3 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2b |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IHC-P, IF, FACS |
| Application Details | Western blot: 0.5-1ug/ml, Immunohistochemistry (FFPE): 2-5ug/ml, Immunofluorescence: 5ug/ml, Flow cytometry: 1-3ug/million cells |
| Application Note | Optimal dilution of the CANX antibody should be determined by the researcher. |
| Localization | Cytoplasmic |
| Immunogen | Recombinant human protein (amino acids E68-R582) was used as the immunogen for the CANX antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the CANX antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CANX antibody is available for research use only. |
| Uniprot # | P27824 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/canx-antibody-calnexin-8d10b3-rq7262 |
| Title | CANX Antibody / Calnexin |
| Description | Calnexin, also called CANX and CNX, is a 67 kDa integral protein of the endoplasmic reticulum. This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. |
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