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NSJ Bioreagents
SKU:RQ6538
Calpain 1 Antibody / CAPN1
Calpain 1 Antibody / CAPN1
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CAPN1 is also known as CANP or muCL. The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Clone | 2I10 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2a |
| Species Reactivity | Human |
| Application | WB, IF, FACS |
| Application Details | Western blot: 1-2ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/million cells |
| Application Note | Optimal dilution of the Calpain 1 antibody should be determined by the researcher. |
| Localization | Cytoplasm, cell membrane |
| Immunogen | An E. coli-derived human protein (amino acids Q396-A555) was used as the immunogen for the Calpain 1 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Affinity purified |
| Storage | After reconstitution, the Calpain 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This Calpain 1 antibody is available for research use only. |
| Uniprot # | P07384 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/calpain-1-antibody-capn1-2i10-rq6538 |
| Title | Calpain 1 Antibody / CAPN1 |
| Description | CAPN1 is also known as CANP or muCL. The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. |
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