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NSJ Bioreagents
SKU:F54849-0.08ML
Calcipressin-2 Antibody / RCAN2 / DSCR1L1
Calcipressin-2 Antibody / RCAN2 / DSCR1L1
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Calcipressin-2/DSCR1L1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. This protein may play a role during central nervous system development. Expression is detected in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas. Expression of both transcripts is upregulated by physiologic concentrations of the thyroid hormone triiodothyroxine.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | FACS, IHC-P, WB |
| Application Details | Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:10-1:50, Western blot: 1:500-1:1000 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the Calcipressin-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic, nuclear |
| Immunogen | A portion of amino acids 6-37 from the human protein was used as the immunogen for the Calcipressin-2 antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the Calcipressin-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Calcipressin-2 antibody is available for research use only. |
| Uniprot # | Q14206 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/calcipressin-2-antibody-rcan2-dscr1l1-f54849 |
| Title | Calcipressin-2 Antibody / RCAN2 / DSCR1L1 |
| Description | Calcipressin-2/DSCR1L1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. This protein may play a role during central nervous system development. Expression is detected in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas. Expression of both transcripts is upregulated by physiologic concentrations of the thyroid hormone triiodothyroxine. |
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