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NSJ Bioreagents

SKU:R32474

CA2 Antibody / Carbonic Anhydrase 2

CA2 Antibody / Carbonic Anhydrase 2

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CA2 is a cytosolic enzyme with the highest activity among all known CAs. The carbonic anhydrases (ACs) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification. This gene is mapped to 8q22.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB, IHC-P, FACS
Application Details Western blot: 0.5-1ug/ml,IHC (FFPE): 1-2ug/ml,FACS: 1-3ug/10^6 cells
Application Note Optimal dilution of the CA2 antibody should be determined by the researcher.
Localization Cytoplasmic, nuclear
Immunogen Amino acids S2-K260 from the human protein were used as the immunogen for the CA2 antibody.
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Purity Antigen affinity
Storage Prior to reconstitution, store at 4oC. After reconstitution, the CA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This CA2 antibody is available for research use only.
Uniprot # P00918
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/ca2-antibody-carbonic-anhydrase-2-r32474
Title CA2 Antibody / Carbonic Anhydrase 2
Description CA2 is a cytosolic enzyme with the highest activity among all known CAs. The carbonic anhydrases (ACs) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification. This gene is mapped to 8q22.
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