• Flow cytometry testing of fixed and permeabilized human HEL cells with C-C chemokine receptor type 4 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= C-C chemokine receptor type 4 antibody.
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NSJ Bioreagents

RQ8008

C-C chemokine receptor type 4 Antibody / CCR4

C-C chemokine receptor type 4 Antibody / CCR4

$449.00 USD
$449.00 USD
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CCR4, or C-C chemokine receptor type 4, is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194 (cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines. The CCR4 gene is mapped to chromosome 3. Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB, FACS, Direct ELISA
Application Details Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note Optimal dilution of the C-C chemokine receptor type 4 antibody should be determined by the researcher.
Immunogen E. coli-derived recombinant human protein (amino acids L267-H296) was used as the immunogen for the C-C chemokine receptor type 4 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity purified
Storage After reconstitution, the C-C chemokine receptor type 4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This C-C chemokine receptor type 4 antibody is available for research use only.
Uniprot # P51679
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/c-c-chemokine-receptor-type-4-antibody-ccr4-rq8008
Title C-C chemokine receptor type 4 Antibody / CCR4
Description CCR4, or C-C chemokine receptor type 4, is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194 (cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines. The CCR4 gene is mapped to chromosome 3. Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
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