• Western blot testing of 1) rat kidney, 2) rat liver, 3) mouse liver and 4) human HeLa lysate with BRMS1 antibody at 0.5ug/ml. Predicted molecular weight ~28 kDa, often observed at ~35 kDa.
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NSJ Bioreagents

R32791

BRMS1 Antibody

BRMS1 Antibody

$449.00 USD
$449.00 USD
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Breast cancer metastasis-suppressor 1 is a protein that in humans is encoded by the BRMS1 gene. This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB
Application Details Western blot: 0.5-1ug/ml
Application Note Optimal dilution of the BRMS1 antibody should be determined by the researcher.
Immunogen Amino acids D52-D244 from the human protein were used as the immunogen for the BRMS1 antibody.
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Purity Antigen affinity
Storage After reconstitution, the BRMS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This BRMS1 antibody is available for research use only.
Uniprot # Q9HCU9
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/brms1-antibody-r32791
Title BRMS1 Antibody
Description Breast cancer metastasis-suppressor 1 is a protein that in humans is encoded by the BRMS1 gene. This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
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