• IHC testing of FFPE human lung cancer tissue with BRD7 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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NSJ Bioreagents

RQ4286

BRD7 Antibody

BRD7 Antibody

$449.00 USD
$449.00 USD
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Bromodomain-containing protein 7 is a protein that in humans is encoded by the BRD7 gene. This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human
Application WB, IHC-P, ELISA
Application Details Western blot: 0.5-1ug/ml, IHC (FFPE): 1-2ug/ml, Direct ELISA: 0.1-0.5ug/ml
Application Note Optimal dilution of the BRD7 antibody should be determined by the researcher.
Localization Predominantly nuclear
Immunogen A recombinant human protein corresponding to amino acids T514-R567 was used as the immunogen for the BRD7 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Purity Antigen affinity purified
Storage After reconstitution, the BRD7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This BRD7 antibody is available for research use only.
Uniprot # Q9NPI1
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/brd7-antibody-rq4286
Title BRD7 Antibody
Description Bromodomain-containing protein 7 is a protein that in humans is encoded by the BRD7 gene. This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
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