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NSJ Bioreagents

SKU:F53770-0.08ML

BRD4 Antibody (N-Terminal Region)

BRD4 Antibody (N-Terminal Region)

Regular price $205.00 USD
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BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people.

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Application IHC, ELISA
Application Details IHC (Paraffin): 1:50-1:100
Application Note Titration of the BRD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Immunogen A portion of amino acids 1-30 from the human protein was used as the immunogen for this BRD4 antibody.
Purity Purified
Storage Aliquot the BRD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This BRD4 antibody is available for research use only.
Uniprot # O60885
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/brd4-antibody-n-terminal-region-f53770
Title BRD4 Antibody (N-Terminal Region)
Description BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people.
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