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NSJ Bioreagents
SKU:F53771-0.08ML
BRD4 Antibody (C-Terminal Region)
BRD4 Antibody (C-Terminal Region)
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$205.00 USD
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BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Predicted Species Reactivity | Mouse |
| Application | IHC, ELISA |
| Application Details | IHC (Paraffin): 1:50-1:100 |
| Application Note | Titration of the BRD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 1313-1342 from the human protein was used as the immunogen for this BRD4 antibody. |
| Purity | Purified |
| Storage | Aliquot the BRD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This BRD4 antibody is available for research use only. |
| Uniprot # | O60885 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/brd4-antibody-c-terminal-region-f53771 |
| Title | BRD4 Antibody (C-Terminal Region) |
| Description | BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. |
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