• Flow cytometry testing of human MCF7 cells with BRCA1-Associated Protein 1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= BRCA1-Associated Protein 1 antibody.
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NSJ Bioreagents

RQ6826

BRCA1-Associated Protein 1 / BAP1

BRCA1-Associated Protein 1 / BAP1

$449.00 USD
$449.00 USD
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BAP1, also known as BRCA1-associated protein-1, contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals. BAP1 is a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. BAP1 is expressed as a 4-kb mRNA in all human tissues, and mapped to 3p21.3.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human
Application WB, FACS, Direct ELISA
Application Details Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note Optimal dilution of the BRCA1-Associated Protein 1 antibody should be determined by the researcher.
Immunogen Recombinant human protein (amino acids E7-Q702) was used as the immunogen for the BRCA1-Associated Protein 1 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity purified
Storage After reconstitution, the BRCA1-Associated Protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This BRCA1-Associated Protein 1 antibody is available for research use only.
Uniprot # Q92560
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/brca1-associated-protein-1-bap1-rq6826
Title BRCA1-Associated Protein 1 / BAP1
Description BAP1, also known as BRCA1-associated protein-1, contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals. BAP1 is a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. BAP1 is expressed as a 4-kb mRNA in all human tissues, and mapped to 3p21.3.
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