NSJ Bioreagents
SKU:RQ6758
BPIFA1 Antibody / SPLUNC1 / PLUNC
BPIFA1 Antibody / SPLUNC1 / PLUNC
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Palate, lung, and nasal epithelium clone protein (PLUNC) is a gene encoding a secretory protein. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse |
| Application | WB, Direct ELISA |
| Application Details | Western blot: 1-2ug/ml,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the BPIFA1 antibody should be determined by the researcher. |
| Immunogen | Recombinant human protein (amino acids L64-V256) was used as the immunogen for the BPIFA1 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the BPIFA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This BPIFA1 antibody is available for research use only. |
| Uniprot # | Q9NP55 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/bpifa1-antibody-splunc1-plunc-rq6758 |
| Title | BPIFA1 Antibody / SPLUNC1 / PLUNC |
| Description | Palate, lung, and nasal epithelium clone protein (PLUNC) is a gene encoding a secretory protein. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. |
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