• Western blot testing of 1) human HepG2, 2) human U-2 OS, 3) human Caco-2, 4) rat lung and 5) mouse lung tissue lysate with BMP4 antibody at 0.5ug/ml. Expected molecular weight: 54 kDa (precursor), 44 kDa (cleaved dimer), 23 kDa (cleaved monomer).
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NSJ Bioreagents

R32828

BMP4 Antibody / Bone morphogenetic protein 4

BMP4 Antibody / Bone morphogenetic protein 4

$449.00 USD
$449.00 USD
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Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. It is found on chromosome 14q22-q23. The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB, ELISA (capture)
Application Details Western Blot: 0.5-1ug/ml,ELISA (Capture; human recombinant protein): 0.1-0.5ug/ml (BSA-free formulation available)
Application Note Optimal dilution of the BMP4 antibody should be determined by the researcher.
Immunogen A recombinant human protein corresponding to amino acids S293-R408 was used as the immunogen for the BMP4 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity
Storage After reconstitution, the BMP4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This BMP4 antibody is available for research use only.
Uniprot # P12644
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/bmp4-antibody-r32828
Title BMP4 Antibody / Bone morphogenetic protein 4
Description Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. It is found on chromosome 14q22-q23. The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
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