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NSJ Bioreagents
SKU:RQ5386
BMP2 Antibody / Bone morphogenetic protein 2
BMP2 Antibody / Bone morphogenetic protein 2
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The BMP2 gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [RefSeq]
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | AOHD-2 |
| Host Animal | Rabbit |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB |
| Application Details | Western blot: 1:500-1:2000 |
| Application Note | Optimal dilution of the BMP2 antibody should be determined by the researcher. |
| Immunogen | A synthetic peptide specific to human BMP2 was used as the immunogen for the BMP2 antibody. |
| Purity | Affinity purified |
| Storage | Store the BMP2 antibody at -20oC. |
| Limitation | This BMP2 antibody is available for research use only. |
| Uniprot # | P12643 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/bmp2-antibody-bone-morphogenetic-protein-2-aohd-2-rq5386 |
| Title | BMP2 Antibody / Bone morphogenetic protein 2 |
| Description | The BMP2 gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [RefSeq] |
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