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NSJ Bioreagents
SKU:F54739-0.08ML
Bleomycin hydrolase Antibody / BLMH
Bleomycin hydrolase Antibody / BLMH
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$205.00 USD
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The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse, Rat |
| Application | IHC-P, WB |
| Application Details | Immunohistochemistry (FFPE): 1:25, Western blot: 1:500-1:1000 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the Bleomycin hydrolase antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic |
| Immunogen | A portion of amino acids 212-242 from the human protein was used as the immunogen for the Bleomycin hydrolase antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the Bleomycin hydrolase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Bleomycin hydrolase antibody is available for research use only. |
| Uniprot # | Q13867 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/bleomycin-hydrolase-antibody-blmh-f54739 |
| Title | Bleomycin hydrolase Antibody / BLMH |
| Description | The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity). |
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