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NSJ Bioreagents
SKU:RQ7366
BI-1 Antibody / Bax inhibitor 1 / TMBIM6
BI-1 Antibody / Bax inhibitor 1 / TMBIM6
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Bax inhibitor 1 (BI-1) is a protein that in humans is encoded by the TMBIM6 gene. Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process; negative regulation of intrinsic apoptotic signaling pathway; and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P, IF |
| Application Details | Western blot: 0.5-1ug/ml, Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence: 5ug/ml |
| Application Note | Optimal dilution of the BI-1 antibody should be determined by the researcher. |
| Localization | Cytoplasmic (ER) |
| Immunogen | Amino acids RKINFDALLKFSHITPSTQQHLK were used as the immunogen for the BI-1 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the BI-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This BI-1 antibody is available for research use only. |
| Uniprot # | P55061 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/bi-1-antibody-bax-inhibitor-1-tmbim6-rq7366 |
| Title | BI-1 Antibody / Bax inhibitor 1 / TMBIM6 |
| Description | Bax inhibitor 1 (BI-1) is a protein that in humans is encoded by the TMBIM6 gene. Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process; negative regulation of intrinsic apoptotic signaling pathway; and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma. |
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