NSJ Bioreagents
SKU:RQ6827
BEX3 Antibody / NGFRAP1 / NADE
BEX3 Antibody / NGFRAP1 / NADE
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Protein BEX3 is a protein that in humans is encoded by the BEX3 gene. BEX3 (brain-expressed X-linked protein 3), also called NGFRAP1 (nerve growth factor receptor associated protein 1), NADE (p75NTR-associated death executor) or FAP-1 (Fas-associated phosphatase-1), is a 24 kDa member of the BEX protein family. A nuclear export signal (aa 77-87) allows NGFRAP1 to export bound p75NTR. It is widely expressed, but highest in ovarian granulosa cells, testis, prostate, seminal vesicle and liver. Except for a 13-19 amino acid (aa) rodent Arg/His region at aa 35 that is not found in humans, human NGFRAP1 shares 94% aa identity with mouse and rat NGFRAP1. In humans, a 101 aa isoform with an alternative start site at aa 11 has been described.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, FACS, Direct ELISA |
| Application Details | Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the BEX3 antibody should be determined by the researcher. |
| Immunogen | Recombinant human protein (amino acids Q39-H103) was used as the immunogen for the BEX3 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the BEX3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This BEX3 antibody is available for research use only. |
| Uniprot # | Q00994 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/bex3-antibody-ngfrap1-nade-rq6827 |
| Title | BEX3 Antibody / NGFRAP1 / NADE |
| Description | Protein BEX3 is a protein that in humans is encoded by the BEX3 gene. BEX3 (brain-expressed X-linked protein 3), also called NGFRAP1 (nerve growth factor receptor associated protein 1), NADE (p75NTR-associated death executor) or FAP-1 (Fas-associated phosphatase-1), is a 24 kDa member of the BEX protein family. A nuclear export signal (aa 77-87) allows NGFRAP1 to export bound p75NTR. It is widely expressed, but highest in ovarian granulosa cells, testis, prostate, seminal vesicle and liver. Except for a 13-19 amino acid (aa) rodent Arg/His region at aa 35 that is not found in humans, human NGFRAP1 shares 94% aa identity with mouse and rat NGFRAP1. In humans, a 101 aa isoform with an alternative start site at aa 11 has been described. |
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