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NSJ Bioreagents
SKU:F54948-0.08ML
Beta-nerve growth factor Antibody / NGF
Beta-nerve growth factor Antibody / NGF
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NGFB is a member of the NGF-beta family. It is a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in the gene encoding NGFB have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of the gene's expression is associated with allergic rhinitis.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | IF, FACS, IHC-P, WB |
| Application Details | Immunofluorescence: 1:10-1:50, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:10-1:50, Western blot: 1:500-1:1000 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the Beta-nerve growth factor antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic, secreted |
| Immunogen | A portion of amino acids 84-115 from the human protein was used as the immunogen for the Beta-nerve growth factor antibody. |
| Purity | Purified |
| Storage | Aliquot the Beta-nerve growth factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Beta-nerve growth factor antibody is available for research use only. |
| Uniprot # | P01138 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/beta-nerve-growth-factor-antibody-ngf-f54948 |
| Title | Beta-nerve growth factor Antibody / NGF |
| Description | NGFB is a member of the NGF-beta family. It is a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in the gene encoding NGFB have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of the gene's expression is associated with allergic rhinitis. |
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