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NSJ Bioreagents
SKU:F55031-0.08ML
Beta Glucuronidase Antibody / Gusb
Beta Glucuronidase Antibody / Gusb
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The GUSB gene encodes beta-glucuronidase, a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987). The GUSB gene is mutated in mucopolysaccharidosis type VII.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | IHC-P, FACS, WB |
| Application Details | Immunohistochemistry (FFPE): 1:50-1:100, Flow cytometry: 1:10-1:50 (1x10e6 cells), Western blot: 1:2000-1:4000 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the Beta Glucuronidase antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic |
| Immunogen | A portion of amino acids 335-362 from the human protein was used as the immunogen for the Beta Glucuronidase antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the Beta Glucuronidase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Beta Glucuronidase antibody is available for research use only. |
| Uniprot # | P08236 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/beta-glucuronidase-antibody-gusb-f55031 |
| Title | Beta Glucuronidase Antibody / Gusb |
| Description | The GUSB gene encodes beta-glucuronidase, a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987). The GUSB gene is mutated in mucopolysaccharidosis type VII. |
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