NSJ Bioreagents
SKU:FY12010
BCL2L15 Antibody / BCL2 like protein 15
BCL2L15 Antibody / BCL2 like protein 15
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BCL2L15 antibody targets BCL2 like protein 15, a member of the BCL2 family of apoptosis regulators. Unlike classical anti-apoptotic proteins such as BCL2 and BCL2L1, BCL2L15 is less characterized but is thought to modulate apoptosis-related signaling. Expression has been detected in reproductive tissues, including ovary and testis, suggesting a role in germ cell survival and differentiation. Structural features align it with pro-survival BCL2 proteins, although functional studies remain ongoing.<br><br>Research using BCL2L15 antibody has begun to explore how this protein influences cell fate. BCL2 family members are critical checkpoints in the balance between cell death and survival, and alterations in their expression often contribute to tumorigenesis or developmental disorders. Preliminary studies suggest BCL2L15 may serve tissue-specific roles, particularly in regulating apoptosis during gametogenesis and early embryonic development.<br><br>Validated antibody clones enable applications such as western blot, immunohistochemistry, and immunofluorescence, providing researchers with reliable detection of this lesser-studied family member. These tools are important for mapping BCL2L15 expression patterns and clarifying its biological function within the apoptotic network.<br><br>NSJ Bioreagents provides this BCL2L15 antibody to support investigations into apoptosis regulation, reproduction biology, and cancer pathways. Alternate names include BCL2 like protein 15 antibody, BFK antibody, and BCL2 related protein F antibody.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Format | Liquid |
| Clone | 31B01 |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC, ICC, IF, FACS |
| Application Details | Western blot: 1:500-1:2000,Immunohistochemistry: 1:50-1:200,Immunocytochemistry/Immunofluorescence: 1:50-1:200,Flow Cytometry: 1:50 |
| Application Note | Optimal dilution of the BCL2L15 antibody should be determined by the researcher. |
| Immunogen | A synthesized peptide derived from human BCL2L15 was used as the immunogen for the BCL2L15 antibody. |
| Buffer | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Purity | Affinity-chromatography |
| Storage | Store the BCL2L15 antibody at -20oC. |
| Limitation | This BCL2L15 antibody is available for research use only. |
| Uniprot # | Q5TBC7 |
| Status | Available |
| PDF Link | http://www.nsjbio.com/tds-pdf/bcl2l15-antibody-bcl2-like-protein-15-fy12010-nsj-bioreagents |
| Title | BCL2L15 Antibody / BCL2 like protein 15 |
| Description | BCL2L15 antibody targets BCL2 like protein 15, a member of the BCL2 family of apoptosis regulators. Unlike classical anti-apoptotic proteins such as BCL2 and BCL2L1, BCL2L15 is less characterized but is thought to modulate apoptosis-related signaling. Expression has been detected in reproductive tissues, including ovary and testis, suggesting a role in germ cell survival and differentiation. Structural features align it with pro-survival BCL2 proteins, although functional studies remain ongoing.<br><br>Research using BCL2L15 antibody has begun to explore how this protein influences cell fate. BCL2 family members are critical checkpoints in the balance between cell death and survival, and alterations in their expression often contribute to tumorigenesis or developmental disorders. Preliminary studies suggest BCL2L15 may serve tissue-specific roles, particularly in regulating apoptosis during gametogenesis and early embryonic development.<br><br>Validated antibody clones enable applications such as western blot, immunohistochemistry, and immunofluorescence, providing researchers with reliable detection of this lesser-studied family member. These tools are important for mapping BCL2L15 expression patterns and clarifying its biological function within the apoptotic network.<br><br>NSJ Bioreagents provides this BCL2L15 antibody to support investigations into apoptosis regulation, reproduction biology, and cancer pathways. Alternate names include BCL2 like protein 15 antibody, BFK antibody, and BCL2 related protein F antibody. |
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