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NSJ Bioreagents
SKU:F54977-0.08ML
Bcl-2-like protein 11 Antibody / BCL2L11 / Bim
Bcl-2-like protein 11 Antibody / BCL2L11 / Bim
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$205.00 USD
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Bcl-2-like protein 11, also called BCL2L11 and Bim, belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | IHC-P, FACS, WB |
| Application Details | Immunohistochemistry (FFPE): 1:25, Flow cytometry: 1:50-1:100 (1x10e6 cells), Western blot: 1:500-1:1000 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the Bcl-2-like protein 11 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic |
| Immunogen | A portion of amino acids 134-160 from the human protein was used as the immunogen for the Bcl-2-like protein 11 antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the Bcl-2-like protein 11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Bcl-2-like protein 11 antibody is available for research use only. |
| Uniprot # | O43521 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/bcl-2-like-protein-11-antibody-bcl2l11-bim-f54977 |
| Title | Bcl-2-like protein 11 Antibody / BCL2L11 / Bim |
| Description | Bcl-2-like protein 11, also called BCL2L11 and Bim, belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. |
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