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NSJ Bioreagents
SKU:RQ7211
BBS8 Antibody / Bardet-Biedl syndrome 8 / TTC8
BBS8 Antibody / Bardet-Biedl syndrome 8 / TTC8
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Tetratricopeptide repeat domain 8 (TTC8) also known as Bardet-Biedl syndrome 8 (BBS8) is a protein that in humans is encoded by the TTC8 gene. This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. A mutation in this gene has also been implicated in nonsyndromic retinitis pigmentosa. Alternative splicing results in multiple transcript variants.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, FACS, Direct ELISA |
| Application Details | Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the BBS8 antibody should be determined by the researcher. |
| Immunogen | Recombinant human protein (amino acids E271-Q533) was used as the immunogen for the BBS8 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the BBS8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This BBS8 antibody is available for research use only. |
| Uniprot # | Q8TAM2 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/bbs8-antibody-bardet-biedl-syndrome-8-ttc8-rq7211 |
| Title | BBS8 Antibody / Bardet-Biedl syndrome 8 / TTC8 |
| Description | Tetratricopeptide repeat domain 8 (TTC8) also known as Bardet-Biedl syndrome 8 (BBS8) is a protein that in humans is encoded by the TTC8 gene. This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. A mutation in this gene has also been implicated in nonsyndromic retinitis pigmentosa. Alternative splicing results in multiple transcript variants. |
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