• Western blot testing of 1) human HeLa, 2) human ThP-1, 3) human U-87 MG, 4) rat brain, 5) rat heart, 6) rat lung, 7) rat liver, 8) mouse brain, 9) mouse heart and 10) mouse lung lysate with BAG6 antibody at 0.5ug/ml. Predicted molecular weight ~119 kDa but observed at 150-170 kDa.
1 1

NSJ Bioreagents

RQ4907

BAG6 Antibody / BAT3

BAG6 Antibody / BAT3

$449.00 USD
$449.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

Large proline-rich protein BAG6 is a protein that in humans is encoded by the BAG6 gene. It is mapped to 6p21.33. This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB, IHC-P, IF, FACS, Direct ELISA
Application Details Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/10^6 cells,Direct ELISA: 0.1-0.5ug/ml
Application Note Optimal dilution of the BAG6 Antibody should be determined by the researcher.
Localization Cytoplasmic, nuclear
Immunogen Amino acids D15-A88 from the human protein were used as the immunogen for the BAG6 Antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Purity Antigen affinity purified
Storage After reconstitution, the BAG6 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This BAG6 Antibody is available for research use only.
Uniprot # P46379
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/bag6-antibody-bat3-rq4907
Title BAG6 Antibody / BAT3
Description Large proline-rich protein BAG6 is a protein that in humans is encoded by the BAG6 gene. It is mapped to 6p21.33. This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
View full details