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NSJ Bioreagents
SKU:F55107-0.08ML
B2AR Antibody / Beta-2-Adrenergic receptor / ADRB2
B2AR Antibody / Beta-2-Adrenergic receptor / ADRB2
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$205.00 USD
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The Beta-2-Adrenergic receptor is a protein that is found on the surface of cells, particularly in the lungs, heart, and smooth muscle tissue. It is a member of the G-protein coupled receptor family which transmits signals from outside the cell to the inside, triggering a cascade of cellular responses. The Beta-2-Adrenergic receptor plays a critical role in regulating various physiological functions, including bronchodilation, heart rate, and glucose metabolism. Dysregulation of the Beta-2-Adrenergic receptor has been implicated in a variety of diseases, such as asthma, chronic obstructive pulmonary disease, and heart failure.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Application Details | Western blot: 1:1000-1:2000,Immunohistochemistry (FFPE): 1:10-1:50 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the B2AR antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cell membrane, cytoplasm |
| Immunogen | A portion of amino acids 236-264 from the human protein was used as the immunogen for the B2AR antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the B2AR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This B2AR antibody is available for research use only. |
| Uniprot # | P07550 |
| Status | Available |
| PDF Link | http://www.nsjbio.com/tds-pdf/b2ar-antibody-beta-2-adrenergic-receptor-adrb2-f55107 |
| Title | B2AR Antibody / Beta-2-Adrenergic receptor / ADRB2 |
| Description | The Beta-2-Adrenergic receptor is a protein that is found on the surface of cells, particularly in the lungs, heart, and smooth muscle tissue. It is a member of the G-protein coupled receptor family which transmits signals from outside the cell to the inside, triggering a cascade of cellular responses. The Beta-2-Adrenergic receptor plays a critical role in regulating various physiological functions, including bronchodilation, heart rate, and glucose metabolism. Dysregulation of the Beta-2-Adrenergic receptor has been implicated in a variety of diseases, such as asthma, chronic obstructive pulmonary disease, and heart failure. |
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