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NSJ Bioreagents
SKU:F54328-0.05ML
Autotaxin Antibody / ENPP2
Autotaxin Antibody / ENPP2
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$205.00 USD
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ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, FACS |
| Application Details | Western blot: 1:500-1:2000,Flow cytometry: 1:25 (1x10e6 cells) |
| Application Note | The stated application concentrations are suggested starting points. Titration of the Autotaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 377-406 from the human protein was used as the immunogen for the Autotaxin antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the Autotaxin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Autotaxin antibody is available for research use only. |
| Uniprot # | Q13822 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/autotaxin-antibody-enpp2-f54328 |
| Title | Autotaxin Antibody / ENPP2 |
| Description | ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form. |
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