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NSJ Bioreagents
SKU:F53855-0.05ML
Atrogin 1 Antibody / FBXO32
Atrogin 1 Antibody / FBXO32
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F-box only protein 32 / Atrogin 1 is a substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Predicted Species Reactivity | Bovine, Mouse, Pig, Rat |
| Application | WB |
| Application Details | Western blot: 1:1000-2000 |
| Application Note | Titration of the Atrogin 1 antibody may be required due to differences in protocols and substrate sensitivity. |
| Immunogen | A portion of amino acids 17-49 from the human protein was used as the immunogen for the Atrogin 1 antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the Atrogin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Atrogin 1 antibody is available for research use only. |
| Uniprot # | Q969P5 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/atrogin-1-antibody-fbxo32-f53855 |
| Title | Atrogin 1 Antibody / FBXO32 |
| Description | F-box only protein 32 / Atrogin 1 is a substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. |
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