NSJ Bioreagents
SKU:RQ8899
ATRIP Antibody / ATR-interacting protein
ATRIP Antibody / ATR-interacting protein
Couldn't load pickup availability
ATR-interacting protein (ATRIP) is a key regulator of the DNA damage response, functioning as an essential partner of the ATR kinase. ATRIP binds to replication protein A-coated single-stranded DNA and recruits ATR to sites of DNA damage or replication stress, initiating checkpoint signaling that maintains genome stability. <p>ATRIP plays a vital role in coordinating cell cycle arrest and DNA repair processes in response to genotoxic stress. Defects in ATRIP function can compromise DNA damage checkpoint activation, leading to genomic instability and contributing to developmental abnormalities and disease susceptibility. <p>Using a high-quality ATRIP antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunoprecipitation. An ATRIP antibody from NSJ Bioreagents ensures consistent and reproducible results for studies in DNA repair, replication stress, and checkpoint signaling. Selecting the right ATRIP antibody is critical for advancing research in genome maintenance and disease mechanisms.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | 26A07 |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Application Details | Western blot: 1:500,Immunohistochemistry (FFPE): 1:50 |
| Application Note | Optimal dilution of the ATRIP antibody should be determined by the researcher. |
| Localization | Nuclear |
| Immunogen | A peptide sequence specific to ATR-interacting protein was used as the immunogen for the ATRIP antibody. |
| Purity | Affinity chromatography |
| Storage | After reconstitution, the ATRIP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This ATRIP antibody is available for research use only. |
| Uniprot # | Q8WXE1 |
| Status | Available |
| PDF Link | http://www.nsjbio.com/tds-pdf/atrip-antibody-atr-interacting-protein-rq8899 |
| Title | ATRIP Antibody / ATR-interacting protein |
| Description | ATR-interacting protein (ATRIP) is a key regulator of the DNA damage response, functioning as an essential partner of the ATR kinase. ATRIP binds to replication protein A-coated single-stranded DNA and recruits ATR to sites of DNA damage or replication stress, initiating checkpoint signaling that maintains genome stability. <p>ATRIP plays a vital role in coordinating cell cycle arrest and DNA repair processes in response to genotoxic stress. Defects in ATRIP function can compromise DNA damage checkpoint activation, leading to genomic instability and contributing to developmental abnormalities and disease susceptibility. <p>Using a high-quality ATRIP antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunoprecipitation. An ATRIP antibody from NSJ Bioreagents ensures consistent and reproducible results for studies in DNA repair, replication stress, and checkpoint signaling. Selecting the right ATRIP antibody is critical for advancing research in genome maintenance and disease mechanisms. |
Share
