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NSJ Bioreagents
SKU:RQ5221
ATP Citrate Lyase Antibody
ATP Citrate Lyase Antibody
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$449.00 USD
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ATP citrate lyase, aslo known as ACLY,is anenzymethat in animals represents an important step infatty acid biosynthesis. ATP citrate lyase is the primary enzyme responsible for the synthesis ofcytosolicacetyl-CoAin many tissues. The enzyme is a tetramer of apparently identical subunits. The product, acetyl-CoA, in animals serves several important biosynthetic pathways, includinglipogenesis andcholesterogenesis.It is activated by insulin. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine.In plants, ATP citrate lyase generates the acetyl-CoA for cytosolically-synthesized metabolites.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Clone | 5I2 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2b |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IHC-P, FACS, IF |
| Application Details | Western blot: 0.1-0.5ug/ml,Immunohistochemistry(FFPE): 0.5-1ug/ml,Flow Cytometry: 1-3ug/1x10^6 cells,Immunofluorescence: 2-4ug/ml |
| Application Note | Optimal dilution of the ATP Citrate Lyase antibody should be determined by the researcher. |
| Immunogen | A human recombinant protein (amino acids M1-I180) was used as the immunogen for the ATP Citrate Lyase antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide |
| Purity | Affinity purified |
| Storage | After reconstitution, the ATP Citrate Lyase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This ATP Citrate Lyase antibody is available for research use only. |
| Uniprot # | P53396 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/atp-citrate-lyase-antibody-5i2-rq5221 |
| Title | ATP Citrate Lyase Antibody |
| Description | ATP citrate lyase, aslo known as ACLY,is anenzymethat in animals represents an important step infatty acid biosynthesis. ATP citrate lyase is the primary enzyme responsible for the synthesis ofcytosolicacetyl-CoAin many tissues. The enzyme is a tetramer of apparently identical subunits. The product, acetyl-CoA, in animals serves several important biosynthetic pathways, includinglipogenesis andcholesterogenesis.It is activated by insulin. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine.In plants, ATP citrate lyase generates the acetyl-CoA for cytosolically-synthesized metabolites. |
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