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NSJ Bioreagents
SKU:RQ6822
Atlastin-1 Antibody / ATL1 / SPG3A
Atlastin-1 Antibody / ATL1 / SPG3A
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Atlastin, or Atlastin-1, is a protein that in humans is encoded by the ATL1 gene. The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P, FACS |
| Application Details | Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells |
| Application Note | Optimal dilution of the Atlastin-1 antibody should be determined by the researcher. |
| Localization | Cytoplasmic |
| Immunogen | Amino acids DKPFLAPNDLQTKHLQ from the human protein were used as the immunogen for the Atlastin-1 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the Atlastin-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This Atlastin-1 antibody is available for research use only. |
| Uniprot # | Q8WXF7 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/atlastin-1-antibody-atl1-spg3a-rq6822 |
| Title | Atlastin-1 Antibody / ATL1 / SPG3A |
| Description | Atlastin, or Atlastin-1, is a protein that in humans is encoded by the ATL1 gene. The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. |
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