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NSJ Bioreagents
SKU:F54547-0.08ML
ATF7IP2 Antibody / MCAF2
ATF7IP2 Antibody / MCAF2
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Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | FACS, IHC-P, WB |
| Application Details | Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE): 1:25, Western blot: 1:500-1:2000 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the ATF7IP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Nuclear |
| Immunogen | A portion of amino acids 318-347 from the human protein was used as the immunogen for the ATF7IP2 antibody . |
| Purity | Antigen affinity purified |
| Storage | Aliquot the ATF7IP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This ATF7IP2 antibody is available for research use only. |
| Uniprot # | Q5U623 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/atf7ip2-antibody-mcaf2-f54547 |
| Title | ATF7IP2 Antibody / MCAF2 |
| Description | Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable). |
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