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NSJ Bioreagents
SKU:F55027-0.08ML
Ataxin 3 Antibody / ATXN3
Ataxin 3 Antibody / ATXN3
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ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, FACS, IHC-P |
| Application Details | Western blot: 1:500-1:1000, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:50-1:100 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the Ataxin 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Nuclear |
| Immunogen | A portion of amino acids 261-288 from the human protein was used as the immunogen for the Ataxin 3 antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the Ataxin 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Ataxin 3 antibody is available for research use only. |
| Uniprot # | P54252 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/ataxin-3-antibody-atxn3-f55027 |
| Title | Ataxin 3 Antibody / ATXN3 |
| Description | ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. |
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