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NSJ Bioreagents
SKU:RQ8350
ASPP1 Antibody / PPP1R13B
ASPP1 Antibody / PPP1R13B
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Apoptosis-stimulating of p53 protein 1 is a protein that in humans is encoded by the PPP1R13B gene. This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, ELISA |
| Application Details | Western blot: 0.5-1ug/ml,ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the ASPP1 antibody should be determined by the researcher. |
| Immunogen | An E.coli-derived human recombinant protein (F901-A1090) was used as the immunogen for the ASPP1 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the ASPP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This ASPP1 antibody is available for research use only. |
| Uniprot # | Q96KQ4 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/aspp1-antibody-ppp1r13b-rq8350 |
| Title | ASPP1 Antibody / PPP1R13B |
| Description | Apoptosis-stimulating of p53 protein 1 is a protein that in humans is encoded by the PPP1R13B gene. This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. |
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