1
/
of
1
NSJ Bioreagents
SKU:F44840-0.08ML
ASIC4 Antibody / ACCN4
ASIC4 Antibody / ACCN4
Regular price
$205.00 USD
Regular price
Sale price
$205.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, ELISA |
| Application Details | Western blot: 1:1000 |
| Application Note | Titration of the ASIC4 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 23-52 from the human protein was used as the immunogen for this ASIC4 antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the ASIC4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This ASIC4 antibody is available for research use only. |
| Uniprot # | Q96FT7 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/asic4-antibody-accn4-f44840 |
| Title | ASIC4 Antibody / ACCN4 |
| Description | This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms. |
Share
