NSJ Bioreagents
SKU:F55126-0.08ML
ASCL2 Antibody / Achaete-scute homolog 2
ASCL2 Antibody / Achaete-scute homolog 2
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ASCL2 belongs to a family of genes that are involved in determining cell fate and differentiation, particularly in the development of tissues such as the nervous system and the intestines. Studies have shown that ASCL2 plays a critical role in regulating the self-renewal and differentiation of stem cells, making it a key player in tissue regeneration and repair processes. One of the most fascinating aspects of ASCL2 is its ability to control the expression of other genes, essentially acting as a master regulator in the cellular development process. By activating or repressing specific genes, ASCL2 can influence the fate of a cell and dictate its ultimate function within a tissue or organ. ASCL2 has been implicated in a variety of diseases and conditions, including certain types of cancers where its dysregulation can lead to uncontrolled cell growth and proliferation.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | WB |
| Application Details | Western blot: 1:500-1:1000 |
| Application Note | The stated application concentrations are suggested starting amounts. Titration of the ASCL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 38-65 from the human protein was used as the immunogen for this ASCL2 antibody. |
| Purity | Antigen affinity |
| Storage | Store at 4oC for up to one month. For long term, aliquot the ASCL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This ASCL2 antibody is available for research use only. |
| Uniprot # | Q96QA5 |
| Status | Available |
| PDF Link | http://www.nsjbio.com/tds-pdf/ascl2-antibody-achaete-scute-homolog-2-f55126 |
| Title | ASCL2 Antibody / Achaete-scute homolog 2 |
| Description | ASCL2 belongs to a family of genes that are involved in determining cell fate and differentiation, particularly in the development of tissues such as the nervous system and the intestines. Studies have shown that ASCL2 plays a critical role in regulating the self-renewal and differentiation of stem cells, making it a key player in tissue regeneration and repair processes. One of the most fascinating aspects of ASCL2 is its ability to control the expression of other genes, essentially acting as a master regulator in the cellular development process. By activating or repressing specific genes, ASCL2 can influence the fate of a cell and dictate its ultimate function within a tissue or organ. ASCL2 has been implicated in a variety of diseases and conditions, including certain types of cancers where its dysregulation can lead to uncontrolled cell growth and proliferation. |
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