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NSJ Bioreagents
SKU:RQ8007
AS3 Antibody / PDS5B
AS3 Antibody / PDS5B
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Sister chromatid cohesion protein PDS5 homolog B (PDS5B), also called Androgen-induced prostate proliferative shutoff-associated protein AS3, or simply 'AS3,' is a protein that in humans is encoded by the PDS5B gene. This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse |
| Application | WB, FACS, Direct ELISA |
| Application Details | Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the AS3 antibody should be determined by the researcher. |
| Immunogen | E. coli-derived recombinant human protein (amino acids Q499-Q1424) was used as the immunogen for the AS3 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the AS3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This AS3 antibody is available for research use only. |
| Uniprot # | Q9NTI5 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/as3-antibody-pds5b-rq8007 |
| Title | AS3 Antibody / PDS5B |
| Description | Sister chromatid cohesion protein PDS5 homolog B (PDS5B), also called Androgen-induced prostate proliferative shutoff-associated protein AS3, or simply 'AS3,' is a protein that in humans is encoded by the PDS5B gene. This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. |
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