• IHC testing of FFPE human skeletal muscle tissue with ARPC1A antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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NSJ Bioreagents

F54854-0.08ML

ARPC1A Antibody

ARPC1A Antibody

$205.00 USD
$205.00 USD
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ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Application FACS, IF, IHC-P, WB
Application Details Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunofluorescence: 1:10-1:50, Immunohistochemistry (FFPE): 1:10-1:50, Western blot: 1:500-1:1000
Application Note The stated application concentrations are suggested starting points. Titration of the ARPC1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Localization Cytoplasmic, nuclear
Immunogen A portion of amino acids 286-315 from the human protein was used as the immunogen for the ARPC1A antibody.
Purity Purified
Storage Aliquot the ARPC1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This ARPC1A antibody is available for research use only.
Uniprot # Q92747
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/arpc1a-antibody-f54854
Title ARPC1A Antibody
Description ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.
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