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NSJ Bioreagents

SKU:RQ4971

ARID2 Antibody / AT-rich interactive domain-containing protein 2

ARID2 Antibody / AT-rich interactive domain-containing protein 2

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AT-rich interactive domain-containing protein 2 (ARID2) is a protein that in humans is encoded by the ARID2 gene. It is mapped to 12q12. This gene encodes a member of the AT-rich interactive domain (ARID)-containing family of DNA-binding proteins. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and chromatin structure modification. This protein functions as a subunit of the polybromo- and BRG1-associated factor or PBAF (SWI/SNF-B) chromatin remodeling complex which facilitates ligand-dependent transcriptional activation by nuclear receptors. Mutations in this gene are associated with hepatocellular carcinomas. A pseudogene of this gene is found on chromosome1.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human
Application WB, IP
Application Details Western blot: 0.5-1ug/ml, Immunoprecipitation: 2ug/500ug of lysate
Application Note Optimal dilution of the ARID2 antibody should be determined by the researcher.
Immunogen Amino acids DERRKGLAFLDELRQFHHSR from the human protein were used as the immunogen for the ARID2 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Affinity purified
Storage Store the ARID2 antibody at -20oC.
Limitation This ARID2 antibody is available for research use only.
Uniprot # Q68CP9
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/arid2-antibody-at-rich-interactive-domain-containing-protein-2-rq4971
Title ARID2 Antibody / AT-rich interactive domain-containing protein 2
Description AT-rich interactive domain-containing protein 2 (ARID2) is a protein that in humans is encoded by the ARID2 gene. It is mapped to 12q12. This gene encodes a member of the AT-rich interactive domain (ARID)-containing family of DNA-binding proteins. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and chromatin structure modification. This protein functions as a subunit of the polybromo- and BRG1-associated factor or PBAF (SWI/SNF-B) chromatin remodeling complex which facilitates ligand-dependent transcriptional activation by nuclear receptors. Mutations in this gene are associated with hepatocellular carcinomas. A pseudogene of this gene is found on chromosome1.
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