• Western blot testing of 1) human SH-SY5Y, 2) human HepG2, 3) human HeLa, 4) rat brain and 5) mouse brain tissue lysate with APLP2 antibody. Predicted molecular weight ~87 kDa, the glycosylated full length and truncated form can be observed at ~120 kDa and ~95 kDa, the CS-GAG modified form can be observed at 130-170 kDa and homodimers and heterodimers may be observed at over 200 kDa.
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NSJ Bioreagents

R30739

APLP2 Antibody

APLP2 Antibody

$449.00 USD
$449.00 USD
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Amyloid beta(A4) precursor-like protein 2, also known as CDEBP, is a protein that in humans is encoded by the APLP2 gene. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. Along with APLP1, it is an important modulator of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB
Application Details Western blot: 0.5-1ug/ml
Application Note The stated application concentrations are suggested starting amounts. Titration of the APLP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Immunogen An amino acid sequence from the C-terminus of human APLP2 (EEKVINSKNKVDENMVID) was used as the immunogen for this APLP2 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity
Storage After reconstitution, the APLP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This APLP2 antibody is available for research use only.
Uniprot # Q06481
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/aplp2-antibody-r30739
Title APLP2 Antibody
Description Amyloid beta(A4) precursor-like protein 2, also known as CDEBP, is a protein that in humans is encoded by the APLP2 gene. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. Along with APLP1, it is an important modulator of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.
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