• Western blot testing of human 1) U-251 MG and 2) U-87 MG cell lysate with APLP1 antibody at 1:2000. Expected molecular weight: 76 kDa (unmodified), ~86 kDa (soluble/glycosylated form), 92~95 kDa (mature form).
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NSJ Bioreagents

F54145-0.05ML

APLP1 Antibody (C-Terminal Region)

APLP1 Antibody (C-Terminal Region)

$205.00 USD
$205.00 USD
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Amyloid-like protein 1 may play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Application WB, FACS
Application Details Western blot: 1:1000-1:2000,Flow cytometry: 1:25 per million cells
Application Note The stated application concentrations are suggested starting points. Titration of the APLP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Immunogen A portion of amino acids 505-539 from human Amyloid-like protein 1 was used as the immunogen for the APLP1 antibody.
Purity Antigen affinity
Storage Aliquot the APLP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This APLP1 antibody is available for research use only.
Uniprot # P51693
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/aplp1-antibody-c-terminal-region-f54145
Title APLP1 Antibody (C-Terminal Region)
Description Amyloid-like protein 1 may play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.
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