1
/
of
1
NSJ Bioreagents
SKU:F47549-0.08ML
AP2 Antibody
AP2 Antibody
Regular price
$205.00 USD
Regular price
Sale price
$205.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
Activator protein 2 is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Predicted Species Reactivity | Bovine, Mouse, Rat |
| Application | WB, ELISA |
| Application Details | Western blot: 1:1000 |
| Application Note | Titration of the AP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 104-133 from the human protein was used as the immunogen for this AP2 antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the AP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This AP2 antibody is available for research use only. |
| Uniprot # | P05549 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/ap2-antibody-f47549 |
| Title | AP2 Antibody |
| Description | Activator protein 2 is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. |
Share
