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NSJ Bioreagents
SKU:F47550-0.08ML
AP2 alpha Antibody (TFAP2A)
AP2 alpha Antibody (TFAP2A)
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$205.00 USD
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Activator protein 2 alpha is expressed in neural crest cell lineages with the highest levels of expression corresponding to early neural crest cells, suggesting that TFAP2A plays a role in their differentiation and development. TFAP2A is expressed in ectoderm and in neural-crest cells migrating from the cranial folds during closure of the neural tube in the mouse. Cranial neural crest cell provides patterning information for craniofacial morphogenesis and generate most of the skull bones and the cranial ganglia.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Predicted Species Reactivity | Bovine |
| Application | WB, ELISA |
| Application Details | Western blot: 1:1000 |
| Application Note | Titration of the AP2 alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 407-436 from the human protein was used as the immunogen for this AP2 alpha antibody. |
| Purity | Purified |
| Storage | Aliquot the AP2 alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This AP2 alpha antibody is available for research use only. |
| Uniprot # | P05549 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/ap2-alpha-antibody-tfap2a-f47550 |
| Title | AP2 alpha Antibody (TFAP2A) |
| Description | Activator protein 2 alpha is expressed in neural crest cell lineages with the highest levels of expression corresponding to early neural crest cells, suggesting that TFAP2A plays a role in their differentiation and development. TFAP2A is expressed in ectoderm and in neural-crest cells migrating from the cranial folds during closure of the neural tube in the mouse. Cranial neural crest cell provides patterning information for craniofacial morphogenesis and generate most of the skull bones and the cranial ganglia. |
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