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NSJ Bioreagents
SKU:F50318-0.08ML
Anti-PCSK9 Antibody
Anti-PCSK9 Antibody
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PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | IHC, FACS, WB, ELISA |
| Application Details | Western blot: 1:1000,IHC (Paraffin): 1:10-1:100,Flow Cytometry: 1:10-1:50 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the anti-PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 479-508 from the human protein was used as the immunogen for this anti-PCSK9 antibody. |
| Purity | Purified |
| Storage | Store at 4oC for up to one month. For long term, aliquot the anti-PCSK9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This anti-PCSK9 antibody is available for research use only. |
| Uniprot # | Q8NBP7 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/anti-pcsk9-antibody-f50318 |
| Title | Anti-PCSK9 Antibody |
| Description | PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. |
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