Skip to product information
1 of 1

NSJ Bioreagents

SKU:F42570-0.08ML

Anti-PAX6 Antibody

Anti-PAX6 Antibody

Regular price $205.00 USD
Regular price Sale price $205.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq].

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Application WB, IHC, IF, ELISA
Application Details Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
Application Note Titration of the anti-PAX6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Localization Nuclear, cytoplasmic
Immunogen This anti-PAX6 antibody was produced from rabbits immunized with a recombinant protein from human PAX6.
Purity Antigen affinity
Storage Aliquot the anti-PAX6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This anti-PAX6 antibody is available for research use only.
Uniprot # P26367
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/anti-pax6-antibody-f42570
Title Anti-PAX6 Antibody
Description This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq].
View full details