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NSJ Bioreagents
SKU:F53585-0.1ML
Anti-Oct4 Antibody
Anti-Oct4 Antibody
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This gene encodes POU5F1/Oct-4/OCT4, a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In ascites with 0.09% sodium azide |
| Format | Ascites |
| Clone | 341CT7.6.2 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgM |
| Species Reactivity | Human, Mouse |
| Application | WB, ELISA |
| Application Details | Western blot: 1:500-1:4000 |
| Application Note | Titration of the anti-Oct4 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | This anti-Oct4 antibody is generated from mouse immunized with POU5F1/OCT4 recombinant protein. |
| Purity | Ascites |
| Storage | Aliquot the anti-Oct4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This anti-Oct4 antibody is available for research use only. |
| Uniprot # | Q01860 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/anti-oct4-antibody-341ct762-f53585 |
| Title | Anti-Oct4 Antibody |
| Description | This gene encodes POU5F1/Oct-4/OCT4, a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. |
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