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NSJ Bioreagents
SKU:F44157-0.08ML
Anti-E Cadherin Antibody
Anti-E Cadherin Antibody
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Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. E Cadherin is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. [UniProt]
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, FACS, ELISA |
| Application Details | Western blot: 1:1000,Flow Cytometry: 1:10-1:50 |
| Application Note | Titration of the anti-E Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic, membranous |
| Immunogen | A portion of amino acids 833-862 from the human protein was used as the immunogen for this anti-E Cadherin antibody. |
| Purity | Purified |
| Storage | Aliquot the anti-E Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This anti-E Cadherin antibody is available for research use only. |
| Uniprot # | P12830 |
| Status | Available |
| PDF Link | http://www.nsjbio.com/tds-pdf/anti-e-cadherin-antibody-f44157 |
| Title | Anti-E Cadherin Antibody |
| Description | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. E Cadherin is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. [UniProt] |
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