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NSJ Bioreagents
SKU:F55041-0.08ML
ANKH Antibody
ANKH Antibody
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$205.00 USD
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ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse |
| Application | FACS, IHC-P, WB |
| Application Details | Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:10-1:50, Western blot: 1:500-1:1000 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the ANKH antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 464-492 from the human protein was used as the immunogen for the ANKH antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the ANKH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This ANKH antibody is available for research use only. |
| Uniprot # | Q9HCJ1 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/ankh-antibody-f55041 |
| Title | ANKH Antibody |
| Description | ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. |
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