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NSJ Bioreagents
SKU:R30129
Angiostatin K1-3 Antibody
Angiostatin K1-3 Antibody
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Ang K1-3 is a proteolytic fragment of Plasminogen. It is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50 = 135nM).
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P, ELISA (protein) |
| Application Details | Western blot: 0.5-1ug/ml,IHC (FFPE): 0.5-1ug/ml,ELISA: 0.1-0.5ug/ml (human protein tested) |
| Application Note | The stated application concentrations are suggested starting amounts. Titration of the Angiostatin K1-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | Human partial recombinant protein (AA 103-352) was used as the immunogen for this Angiostatin K1-3 antibody. |
| Buffer | Lyophilized from 1X PBS with 0.025% sodium azide |
| Purity | Antigen affinity |
| Storage | After reconstitution, the Angiostatin K1-3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This Angiostatin K1-3 antibody is available for research use only. |
| Uniprot # | P00747 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/angiostatin-k1-3-antibody-r30129 |
| Title | Angiostatin K1-3 Antibody |
| Description | Ang K1-3 is a proteolytic fragment of Plasminogen. It is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50 = 135nM). |
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