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NSJ Bioreagents
SKU:RQ6936
Amiloride binding protein 1 Antibody / ABP1 / AOC1
Amiloride binding protein 1 Antibody / ABP1 / AOC1
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This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Monkey |
| Application | WB, IHC-P, IF, FACS, Direct ELISA |
| Application Details | Western blot: 0.5-1 ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the Amiloride binding protein 1 antibody should be determined by the researcher. |
| Localization | Cytoplasmic, membranous |
| Immunogen | Recombinant human protein (amino acids S140-R180) was used as the immunogen for the Amiloride binding protein 1 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the Amiloride binding protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This Amiloride binding protein 1 antibody is available for research use only. |
| Uniprot # | P19801 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/amiloride-binding-protein-1-antibody-abp1-aoc1-rq6936 |
| Title | Amiloride binding protein 1 Antibody / ABP1 / AOC1 |
| Description | This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. |
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