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NSJ Bioreagents
SKU:F44165-0.08ML
Alpha-2-macroglobulin Antibody
Alpha-2-macroglobulin Antibody
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Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Predicted Species Reactivity | Bovine |
| Application | WB, ELISA |
| Application Details | Western blot: 1:1000 |
| Application Note | Titration of the Alpha-2-macroglobulin antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 93-120 from the human protein was used as the immunogen for this Alpha-2-macroglobulin antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the Alpha-2-macroglobulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Alpha-2-macroglobulin antibody is available for research use only. |
| Uniprot # | P01023 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/alpha-2-macroglobulin-antibody-f44165 |
| Title | Alpha-2-macroglobulin Antibody |
| Description | Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq]. |
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